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Topical treatment with WR 279,396 can be compared with topical treatment with Paromomycin Alone in this study, to topical treatment with paromomycin 15% plus methylbenzethonium chloride (MBCL) 12% in the literature, and to treatment with vehicle/no treatment in the literature.
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38 Tacrolimus 0.03% and 0.1% ointments have been compared with topical steroids.
More recently, photodynamic therapy (PDT) with methylaminolaevulinate has been compared with topical imiquimod and topical fluorouracil in a randomised, single-blind study of 601 patients with superficial BCC.
Moreover Armijos and others 3 in 2004 performed a randomized controlled trial in Ecuador in patients with Leishmania guyanensis, Leishmania braziliensis, and Leishmania panamensis NWCL, in which topical paromomycin plus MBCL ointment was compared with topical paromomycin sulphate plus urea, both twice a day for 30 days, compared with meglumine antimoniate for 10 days.
Topical ranibizumab eye drops (2 mg/ml) four times daily for 1 month will be compared with placebo.
Only diclofenac topical solution has been compared with oral diclofenac in head-to-head trials, in which diclofenac topical solution established comparable efficacy and a lower incidence of systemic adverse events compared with oral diclofenac.
The immune response elicited by topical immunization was compared with that elicited by same dose of alum-adsorbed tetanus toxoid (AATT) given intramuscularly.
A total of 174 randomized controlled trials for atopic eczema treatments were identified in which pimecrolimus, tacrolimus, or topical corticosteroids were compared with another intervention or a vehicle/emollient.
First, the mean inhibition diameter for each topical agent was compared with the results of Pirnay et al. [ 12], at the whole population level.
There was no difference in mortality when topical and systemic antibiotic prophylaxis was compared with systemic antibiotic prophylaxis alone (seven studies) and when topical antibiotic prophylaxis was compared with no antibiotic prophylaxis (11 studies).
A topical bimatoprost ocular insert was compared with twice-daily timolol eye drops in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) treated for 6 months.
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