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These results will be compared with expression profiles in other inflammatory rheumatic diseases and further analyzed for dominant pathophysiological pathways in a search for new candidates for targeted therapy in RA.
The same predicted occupancy scores for each PWM and each promoter region sequence can be compared with expression data to determine whether motif occurrences are significantly correlated with expression patterns.
If we are applying our novel algorithm, e.g. to a set of cancer expression profiles that will be compared with expression profiles from a control group, our algorithm computes and outputs the significant paths for each cancer profile (tumor, patient) separately.
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This was compared with expression of CD38 on this subset, currently used in clinical practice as a marker of disease status.
The stem-like cell gene expression is compared with expression in the pre-differentiated stage.
EGFR expression on the tumour cryosections was compared with expression on cryosections of skin and buccal mucosa.
To make a comprehensive evaluation of the consequences at the expression level the array CGH data was compared with expression data obtained by high density expression profiling.
Subsequently, biomarkers' expression values (derived from the DNA microarray data) were compared with expression values for the same genes in slices treated with non-cholestatic drugs.
Immunohistochemical study demonstrated that cytokeratin expression in eccrine spiradenoma was compared with expression in normal eccrine glands and the tubular structures are CEA positive [ 6, 7].
In this study, MPL expression was compared with expression of other genes (EPOR, ERBB2, and IGF1R), which have been widely reported [ 37- 42].
For that reason, expression profiles of pluripotency associated factors in blastemal cells were compared with expression profiles in pluripotent embryonic reference cells.
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