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Therefore, it would be clinically worthwhile to evaluate whether the clinical utility of Calibrated-IBS is maintained even after the risk stratification using this approach.
Therefore, it would be clinically worthwhile to screen patients with asymptomatic CAD (especially those who should be treated with revascularization) in the management of diabetes, although the utility in identifying severe but asymptomatic CAD is still debated.
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We would consider an approximate 25%% relative increase in this rate (hazard ratio [HR] = 0.76) to be clinically worthwhile and feasible; this translates to an estimated 5-year survival of 50%%.
We found that unstimulated intrauterine insemination did not enhance live birth, though the upper limit of the 95% confidence interval for the number needed to treat to benefit was 7, a figure that might be perceived to be clinically worthwhile.
Effect sizes of approximately 0.4 are considered to be clinically worthwhile for back pain interventions [ 23].
For example, designing a trial with favourable power to detect the smallest difference that would be clinically worthwhile using evidence from related studies (e.g. drugs in the same class etc)., ideally taking the uncertainty in the estimation into account [ 28].
Increasing this proportion to 60%% using the AV biofeedback system would be clinically worthwhile.
However, a treatment that benefits only a subset of patients may still be clinically worthwhile.
A 20 percentage point difference in MUVD was chosen because in our judgement such a difference would be clinically worthwhile and the effects on CMD suggest that such a difference is plausible.
This was considered in light of the fact most people in the modern Western world are sedentary and do very little physical activity so a shift in physical activity from very little to a minimum adherence of 50%% of a physical activity intervention is not insignificant and even small changes in behaviour can be clinically worthwhile [ 30].
Adding extra VRBR time to standard rehabilitation also has some benefits; further research is needed to determine if these benefits are clinically worthwhile.
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