Senator Graham said the government could require coverage of more than two brand-name drugs for a particular disease if it was "clinically appropriate" to do so.
Before clinical trials can be considered, drug responses of cell line need to be proven to be clinically appropriate and even before that, high-throughput drug responses for many cell-line studies need to show consistency across labs and publications.
For example, while respondents clearly indicated a preference to be tested for all infections, rather than some, it might not be clinically appropriate or cost-effective to do so in all instances.
Starting the remifentanil infusion at 9 μg/kg per hour (0.15 μg/kg per min) and titrating to 12 μg/kg per hour (0.2 μg/kg per min) before starting the administration of propofol at 0.5 mg/kg per hour (with a bolus dose of up to 0.5 mg/kg) appeared to be clinically appropriate in the present study.
In fact, there is weak evidence in our data of Black men being more likely than White men to undergo those investigations and curative treatments if considered to be clinically appropriate.
Supine blood pressure, supine pulse rate and oral body temperature were measured at specified times and also performed at other times if judged to be clinically appropriate.
Nevertheless, despite these potential limitations, the current study focused on prioritising individuals for surgery assuming surgery was considered to be clinically appropriate.
In those studies, the administration of ototoxic drugs was supposed to be clinically appropriate; inappropriate or uncontrolled drug administration may have shown a different association with hearing loss.
Therefore, classifying these patients as positive and taking into account that they will need further investigation seems to be clinically appropriate in several scenarios.
Some SENs are perceived to be more awkward to work which can result in staff taking safety caps off the devices or taking non-safety needles from other areas where SENs were not deemed to be clinically appropriate.
