Sentence examples for be cleaved to generate from inspiring English sources

The vaccine was designed to allow production of the viral polyprotein, which should be cleaved to generate most of the viral proteins in their mature form; but infectious virus should not be produced.

The extracellular domain of Dlk1 can also be cleaved to generate a soluble form, called fetal antigen 1, which circulates as an abundant growth factor during development [2].

cFLIP can be both pro- and anti-apoptotic [33] but it can be cleaved to generate anti-apoptotic cFLIPp43 that interacts with TRAF2 and induces Nf-κB activation [34].

Full-length chemerin is a proinflammatory protein that can be cleaved to generate antimicrobial peptides and anti-inflammatory species [ 8, 14, 15].

Upon incubation of recombinant human GFAP with caspase 6, we found that GFAP can be cleaved to generate two major degradation products of about 26 and about 24 kDa, respectively.

In many cellular systems undergoing apoptosis, the endogenous PARP 116 kDa protein is cleaved to generate an 89 kDa fragment [24].

It is synthesized as a 2035 amino acid precursor that is cleaved to generate an amino- (HCF-1N) terminal subunit, which promotes G1-to-S phase progression, and a carboxy- (HCF-1C) terminal subunit, which controls multiple aspects of cell division during M phase.

It is produced as a precursor molecule that is cleaved to generate a mature peptide.

SHH is translated as an inactive precursor 45 kDa protein that is cleaved to generate an active 19 kDa isoform.

The pathogenic Atx3Q84 protein runs at ∼73 kDa, and is cleaved to generate fragments running at ∼37 kDa.

Like SHH, MMP9 and 12 are translated as inactive precursor proteins (92 and 55 kDa respectively) that are cleaved to generate active isoforms (84 and 43/22 kDa, respectively).