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These data together suggest that sphingolipid depletion, or the presence of DSBs, does indeed induce a trafficking bottle-neck at the ER to Golgi interface and that this can be circumvented via the expression of ER to Golgi trafficking effectors, rescuing nociceptor function.
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The coupled partial differential equations are solved in a one-dimensional geometry using Laplace transform, and the subsequent coupled ordinary differential equations are circumvented via the method of differential operators.
For preclinical work, this issue is circumvented via the use of 293 cells that stably express Ad5 fiber, yielding an intermediate vector species that is then upscaled using standard 293 cells.
Incomplete conversions, which were attributed to enzyme inhibition by the co-product phenol could be circumvented via in situ co-product removal by scavenging the phenol using the polymeric adsorbent MP-carbonate.
Zoonotic diseases can be circumvented via pathogen-free colonies and additional knockout mutations to disable porcine endogenous retrovirus and prion disease.
Outrageously unfavourable exchange rates imposed by banks when sending money abroad, once unavoidable, can now be circumvented via dozens of online money-changers.No matter which service fintech newcomers "unbundle" from incumbents, the banks' business model will suffer.
The barriers that restrict the applications of the traditional backstepping and approximation-based approach, including the explosion of complexity and the dimension curse problems, are circumvented via dynamic surface control and SPL techniques.
This drawback on IMAC (Fe3+) is circumvented via converting acidic amino acid residues to methyl esters and esterification of the acidic residues prior to the MS analysis.
We postulated that oxidative decomposition could be circumvented if the basic amidine in allyl imino ether 3 would be "protected" via protonation.
These complications can be circumvented by the use of micro-meteorological and remote-sensing techniques for estimating evaporation at the canopy and stand scale via the energy balance.
Expression of XHSF380, a dominant-negative HSF1 mutant, was embryonic lethal, which could be circumvented by delaying expression via a tetracycline inducible promoter.
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