Certain classes of effectors, such as ones modulating host immunity, are believed to rapidly change to overcome resistance, however, the mechanisms generating this variation are not known.
He also cracked the face of his driver Wednesday, so there was that change to overcome too.
D&D represents a world that can be changed, where challenges can be overcome by meeting them head-on.
We recognize that certain aspects of the DNA construct, such as the flap, may not easily be changed, but if these concerns cannot be overcome then the findings could be open to alternative interpretations.
We speculate that these loci are being deregulated epigenetically by chromatin changes to overcome the gene dosage determined by the DNA copy number at the time points tested.
Cells were maintained in induction medium, which was changed every two days to overcome the instability of ascorbic acid in neutral pH.
Based on these results, the product purity in presence of the impurities is analysed and operational and design changes to overcome identified product purity limitations will be presented.
There is a need for systemic change to overcome old paradigms (like the blind pursuit of GDP growth), which have proven inappropriate to tackle global challenges.
The prime minister, who has a modest majority, will move to entrench the Tories' position by pressing ahead with radical boundary changes to overcome what is seen as a bias in favour of Labour.
Although resistance to change is hard to overcome, there is an ongoing paradigm shift.
