A traditional design can, however, be challenged when a pipeline is crossing an earthquake-prone area, when it is constructed in arctic regions, or by the recent advent and use of new high-strength steels.
In 1988, the assumption of the subspecies' extinction was challenged when a hunter shot an adult female, proving the species had somehow survived the war.
Overall, our observation of low reproducibility of urinary BPA excretion over 1 to 3 years indicates evaluation of associations with disease risk in epidemiologic studies may be challenging when only a single spot urine measurement is available.
And has there been enough clarity about how France's social fabric is challenged when an antisemitic show, that of the so-called comedian Dieudonné, gathers millions of positive messages on social media, much of this coming from young people?
Essentially, regressive social norms can be challenged when women play an active and central role within their communities.
Unlike solid cancers with high mutational burdens, or hematologic malignancies where target antigens are expressed homogenously and exclusively by tumor cells, identifying tumor-restricted antigens has been challenging when designing a T-cell targeted therapy for gynecologic tumors.
Even experienced contractors can be challenged when trying to deliver a product that is at once energy efficient and healthy.
In particular, self-reported ethnicity may be challenged when samples have been recruited from a geographic region in which the residents are highly admixed [ 9].
Everything I do is a direct reflection of my parents, which is challenging when you're a woman who challenges normative Arab structures.
The consent process for a genetic study is challenging when the research is conducted in a group stigmatized because of beliefs that the disease is familial.
