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Exact(21)
If a given target has a Bmax value less than 1 nM, it will be challenging to identify PET ligand leads with sufficient potency and alignment of other properties (e.g. PK, NSB).
However, as previously reported, it may be challenging to identify the ligand binding site when the binding energies of the different positions are similar [35].
However, these fractures may be challenging to identify because of osseous overlap; Ogawa et al. (2003) reported that two-thirds of these fractures were missed on initial evaluation.
While these determinants and effects may be challenging to identify in parts of high-income countries, they are patently obvious in many other areas of the world.
The nucleotide and amino acid sequence limitations that cause small proteins to be challenging to identify using homology screens also lead to difficulties in construction of an evolutionary phylogeny.
The research team did not want to oversimplify the many issues, varied experiences and potential contradictions likely to emerge from such a study and anticipated that the impact of drawing on student learning would be challenging to identify and express.
Similar(39)
qRT-PCR requires a suitable reference control gene that is challenging to identify.
Hence, it is challenging to identify these species without prior knowledge of the pathways of catabolism.
The relevance of ( {sigma}_{SCA}^2 ) indicates that it is challenging to identify superior hybrid combinations based on GCA effects.
Ultramarine blue is challenging to identify with XRF techniques due to beam attenuation of the low-energy fluorescence of the lighter elements in air.
It has been challenging to identify core neurocognitive deficits that are consistent across multiple studies in patients with Obsessive Compulsive Disorder (OCD).
More suggestions(15)
proved challenging to identify
be sensitive to identify
be complicated to identify
be challenging to reliably
be challenging to perform
be challenging to start
be challenging to return
be challenging to link
be challenging to use
be challenging to keep
be challenging to build
be challenging to distinguish
be challenging to study
be challenging to manage
be challenging to remember
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com