Sentence examples for be challenging to functionally from inspiring English sources
These differences, while subtle, make EMS more likely to generate coding changes while minimizing non-coding SNVs that can be challenging to functionally dissect.
Third, it can be challenging to produce functionally equal columns.
Obtaining functionally active LBDs of the heteromeric NMDARs has been challenging.
The supramolecular presentation of GAG chains, along with other matrix components, is likely to be functionally important but remains challenging to control and to characterize, both in vivo and in vitro.
The major challenge is to functionally reconstruct the anatomical region; this is crucial in terms of correct mandibular function.
The challenge now is to functionally validate the products of these genes to determine whether they may be used clinically as novel prognostic or predictive biomarkers of breast tumors with poor outcome.
A challenge for future studies will be to functionally dissect the molecular mechanisms by which some of these isoform-specific activities are involved in maintenance not only of epithelial barriers, but also in mediating epithelial-mesenchymal crosstalk during development and maintaining other properties of epithelial cells.
A major challenge facing biosensor development is how to functionally couple a biological recognition domain to an output module so that the binding event can be transduced to a visible and quantifiable signal [e.g., Förster resonance energy transfer (FRET)].
CCR6 expression is restricted to functionally mature memory B cells, capable of responding to antigen challenge [ 30].
In vitro studies were performed to functionally characterize these mutations.
