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Such an approach not infrequently leads to complex models characterized by sophisticated genetic engineering that while biologically informative, may be challenging to effectively implement in therapeutic trials.
With the exception of pharmacologic injection, it can be challenging to effectively administer these various interventions through a side-viewing endoscope; however, endoscopic hemostasis is usually successful.
While it is impossible to project where and when increases in the frequency and intensity of a range of extreme events could occur, it is clear that when they occur (individually or jointly), these events can be challenging to effectively manage.
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They have increasingly become the subject of systematic reviews and are challenging to effectively report.
While storing and hosting big data are certainly possible using today's data storage technology, it is challenging to effectively and efficiently visualize and analyze the data.
Due to the dramatic increase of the scale of modern distributed systems, it is challenging to effectively and efficiently discover the anomalies from a voluminous amount of noisy and high-dimensional data streams.
However, there are challenges to effectively instilling skills to foster continued use after transition to the health workforce.
The first approach involves using different time steps for different particles in relation to their dynamical time scales, leading to an algorithm that is challenging to parallelize effectively.
Pain, being a subjective symptom, is challenging to manage effectively.
Organizations might also be challenged to incorporate gig workers effectively into the teams they'll be working with.
It has been challenging to develop a generalized algorithm to effectively trace both types of chemical plumes due to the significant differences of their kinetic and dynamic properties.
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