Exact(3)
However, it will be challenging to demonstrate a direct link between the species that populate the microbiota and the pathogenesis of pneumonia.
Furthermore, they will need evidence that specific gene-mutation-targeted therapy combinations will provide clinical benefits, which may be challenging to demonstrate with the current paradigm of one-size-fits-all clinical trials.
Long-term cumulative processes may be the drivers for changing dynamics between hosts and pathogens (e.g., generation time, developmental rates, amplification, shifts in seasonal transmission) and create subtle effects that will be challenging to demonstrate in the absence of extensive baselines (4, 6, 7 ).
Similar(54)
3– 6 It is challenging to demonstrate monotherapy efficacy in epilepsy clinical studies.
It has been challenging to demonstrate this competency learnt and internalized by residents even though there are evolving assessment tools specifically focusing on professionalism [ 25- 27].
As can be seen from the model, the relationship between interventions and a wider impact on systems was challenging to demonstrate from the evidence.
As the Park51 community center and mosque project near Ground Zero is painted as an issue of the rights and future of the American Muslim community, Imam Feisal Abdul Rauf has been challenged to demonstrate that he is a moderate voice for Islam.
Although the exact in vivo relationship between these A2B5 expressing glial precursors has been challenging to establish, in vitro studies have demonstrated that GRP can generate oligodendrocyte/type-2 astrocyte progenitor (O-2A) cells and type-1 astrocyte-restricted progenitor (ARP) [21], [28].
Thus, negative results and quantitative differences in defects in response to RNAi against different genes are not interpretable, as it is experimentally challenging to demonstrate quantitative knockdown in the same worm that is scored for subcellular defects and economically not feasible on the scale of the work reported here.
Further, we were challenged to find validated questionnaires that have demonstrated predictive capabilities within the childhood obesity treatment environment.
Christians should be challenged instead to demonstrate how exactly that squares with the other tenets of their faith.
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Justyna Jupowicz-Kozak
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