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And the yeast counterpart to the Werner's syndrome gene does not seem to be central to aging because adding extra copies of it does not enhance life span.
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On the other hand it is questionable whether polar localization is central to aging in bacteria.
DNA damage and repair are central to aging and oncogenesis in higher eukaryotes (1) and to host resistance and antibiotic action in prokaryotes (2).
This did not, however, restore the myofibroblast phenotype, and studies, including our own, have demonstrated that the loss of EGFR expression and its responsiveness in aged cells is central to age-related resistance to differentiation (Shiraha et al., 2000; Simpson et al., 2010).
In addition, the diary would be central to an age-appropriate information pack of existing diabetes and diabetes-related information resources that were considered high quality in terms of content and identified by children and young people in focus groups and interviews as being attractive and relevant to them in terms of content and presentation.
Creatives, journalists and writers will be central to the 'Voice Age'.
Recent work by Vidal et al. provides important insights into the senescence of MSCs that are central to organismal aging.
Telomere biology is central to human aging and cancer, and dissecting the mechanism of telomere protection and telomerase-based telomere elongation at a single molecule level will significantly advance the field.
If protein aggregation is central to bacterial aging, the process of aggregation should also be flexible and responsive to environmental stimuli.
Understanding the aging process is central to preventing age-related disease burden and premature mortality.
Along with home printing, auctions are central to "a new age of the ticket," Mr. Pleasants said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com