Sentence examples for be causative of from inspiring English sources

Therefore, we propose that the single-gene epimutation of unknown cause identified in case iCHD_1 heart DNA could be causative of the abnormal cardiac development through impaired MSX1-dependent mesenchymal embryogenesis.

Within these regions, some genes previously found to be causative of syndromic forms of CL/P have been confirmed, with IRF6 (causing van der Woude Syndrome that usually presents with CL) being the most prominent example, but also some other genes in the TGF β pathway have also been replicated, such as BMP6 [ 70].

Finding a way to prevent telomeres from shortening could help to answer the question; it might also point toward a therapy, if shortened telomeres turn out to be causative of diseases of aging.

As a result, a shift has occurred towards developing and using spontaneous mouse tumor arising in transgenic and/or knockout mice engineered to recapitulate various genetic alterations thought to be causative of specific types of human cancers.

Despite the fact that this digenic inheritance pattern has previously been found to be causative of Usher Syndrome16, and that the variants segregated correctly within our family, there is some controversy with the pathogenicity of this digenism and, as far as we know, the CDH23 and PCDH15 digenism has been only reported in one study16.

"These results contribute to the argument that breastfeeding by itself does not appear to be protective against nut allergy in children, and that it may in fact be causative of allergy," they wrote in the International Journal of Pediatrics.

Nonetheless, disruption of its expression could still be causative of the phenotype.

Moreover, this novel computational method has the potential to identify genes that are causative of metabolomic differences or drug targets.

It is definitively established that mutations in transcription factor HIF-2α are causative of both neuroendocrine tumors (class 1 disease) and polycythemia (class 2 disease).

b)The Inquiry was faced with a complex task in order to determine whether corruption and collusion, racism or institutional lethargy had (alone or in combination) been causative of the seriously flawed initial investigation of the murder.

This includes detecting genetic polymorphism that is causative of phenotype and understanding how genetic variation alters the regulatory network, cell decision and more complex phenotypes.