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SNP assays must be carefully designed because, as Dr Meredith Yeager (NCI, Gaithersburg, MD, USA) pointed out, adjacent SNPs may exist in the region of a targeted SNP that may interfere with primer or probe hybridization and cause misclassification of results.
Such studies need to be carefully designed because of the risk of contamination from placebo effects, but they may provide a more direct answer to the question concerning the importance of optimum vision for elite sporting performance.
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"Every item is carefully designed, because we know people are going to pick it up and look at it," said Livi Vaughan, one of the designers.
Such studies will need to be carefully designed and evaluated because we would not expect these polymorphisms to result in a large difference in circulating hormone levels.
Although conceptually the gas-turbine engine is a simple device, the components for an efficient unit must be carefully designed and manufactured from costly materials because of the high temperatures and stresses encountered during operation.
It is worth emphasizing that the sixteen parameters of T possess only twelve degrees of freedom, as previously discussed and shown explicitly in Figure 6, because statistical algorithms must be carefully designed to be correct with regard to such constraints.
The length of the TTL should be carefully designed.
The force feedback must be carefully designed and calibrated.
Because the energy of sensors is limited, the data-gathering mechanism must be carefully designed to save the energy consumption of sensors to prolong the network lifetime.
Because of cloning's inherent inefficiencies, the nuclear transfer experiments using lymphocytes and other terminally differentiated cells as nuclear donors must be carefully designed and carried out.
To maximize the reliability of WiFi positioning in complex signal environments, the fingerprinting algorithm must be carefully designed to discover a situation in which some of the received signal strength measurements may be miss-scanned because of the prevailing interference.
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CEO of Professional Science Editing for Scientists @ prosciediting.com