After uptake of Salmonella, the DCs matured (data not shown) and were capable to activate both naïve (TN) and memory CD8+ T cells (TMEM), whereas B cells could only reactivate memory CD8+ T cells (Fig. 2E).
These authors have shown that PG is capable to activate colonic fibroblasts leading to growth factors secretion that in turn stimulate colonic epithelial cells.
The subsequent root growth recovery and the concomitant reduction in responsive genes strongly suggest that aspen roots are capable to activate Al tolerance mechanisms when exposed to Al.
Using double-mutants Rac1(G12V, F37L) and Rac1(G12V, Y40H) that are capable to activate different effectors of Rac1, we show that mitochondrial movements are regulated through PAK1 kinase.
In contrast, both sc-tPA and tc-tPA are capable to activate epidermal growth factor receptors (EGFRs), a mechanism mediating the antiapoptotic effects of tPA.
Second, several groups reported the surprising results, that a kinase-defective EGFR was capable to activate downstream signalling (such as MAPK) and stimulate DNA synthesis, while failing to induce the tyrosine phosphorylation of endogenous substrates in response to EGF [ 19- 22].
It is known that during processes such as obesity or atherosclerosis, there are increased levels of proinflammatory cytokines such as IL-6 and TNF-α, which are capable to activate NF-κB in different tissues.
In addition, the data here reported indicate that the thyroid-enriched transcription factor TTF-1 is able to bind in vitro and in vivo the Pax8 far upstream element, and is capable to activate transcription from it.
As shown in Figure 9A, C595scFv-Fc-IL2 C595scFv-Fc-IL2 C595scFv-Fc-IL2s to lysis of MCF7 cells as does IL2 indicating that the fusion protein inducedble to activate resting NK cells.
