An insertion sequence (IS) is a bacterial transposable element that is capable of inserting a new copy of its sequence elsewhere in the genome [ 33].
In 1932, a preadolescent Ceylonese female was documented by British scholars of Tamil mysticism as being capable of inserting into her mouth and down her esophagus both arms to the shoulder, one leg to the groin, and the other leg to just above the patella, and as thereupon able to spin unaided on the orally protrusive knee at rates in excess of 300 r.p.m.
Life on Earth proceeds in an arc — one that began with the big bang, and evolved to the point where a smart teenager is capable of inserting a gene from a cold-water fish into a strawberry, to help protect it from the frost.
They did this by making small holes in the cell walls of individual bacteria and introducing pieces of special DNA, called transposons, through the openings.A transposon is capable of inserting itself more or less at random into another piece of DNA.
In this context it is interesting to note that also many other short, highly cationic and hydrophilic peptides, including the voltage sensor of K+ channels, are capable of inserting and in some cases even passing membranes [20] [22].
Class 1 integrons are capable of inserting, excising and rearranging gene cassettes by a site-specific recombination mechanism.
Due to their disruptive nature, TEs are capable of inserting into multiple sites of a gene, creating a series of TE tagged mutation lines [ 6].
It represents a thermodynamically impressive feat if the BAM complex is capable of inserting into the outer membrane an autotransporter with the huge passenger domain prepositioned on its outer surface (Jain & Goldberg, 2007; Ieva et al., 2008).
Moreover, evidence from patch clamp studies of the action of the Cry1C toxin on Sf cells indicated that this Bt toxin may act inside the cell and is capable of inserting into the cell membrane from the cytoplasmic side [ 40, 41].
For this purpose, atomistic models of 3-D CNT network structures are generated by an automated stochastic algorithm that is capable of randomly inserting CNTs into a design space while controlling several topological parameters including cross-link density, distance between cross-links, as well as length and chirality of CNTs.
These data, summarized in Figures 2(C) and 2(D), indicate that each hydrophobic domain is capable of independently inserting into the membrane.
