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Central hemodynamics will be calculated from peripheral arterial pulse-wave recordings.
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Two other indices of central adiposity were calculated from skinfolds: Central-peripheral (CPR) as subscapular skinfold + suprailliac skinfold)/ (triceps skinfold + thigh skinfold) and ratio of subscapular to triceps skinfold (STR).
Hepatic extraction was calculated from the ratio of peripheral insulin to portal insulin (as calculated from C-peptide) as previously described.
Total peripheral resistance was calculated from CO and BP.
Peripheral subcutaneous fat mass was calculated from the sum of biceps SFT + triceps SFT [ 25, 26].
Peripheral vascular assessment: ABI was calculated from ankle/arm pressure using the Cardio-Vision Model MS-20000; Medical Products Co.s Co., Ltd., San Chung City, Taipei, Taiwan).
Peripheral and tumour aromatase activity and tumour E1 uptake were calculated from levels of H and 14C in purified E1 fractions from tumour and plasma.
is calculated from (9).
were calculated from the models.
Bootstrap values were calculated from 1000 pseudoreplicates.
Mean values were calculated from triplicate reactions.
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