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It is hypothesised that those who complete Stage 3 will have better outcomes than Stage 2 completers who in turn will have better outcomes than those who do not proceed beyond Stage 1. Pre- and post-test differences will be calculated as changes in Quality of Life (SF-12) and Quality Adjusted Life Years (QALYs) SF6D [ 74 ] (calculated from SF-12).
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Absolute annual changes were calculated as changes per 365 days.
In addition, the rate of pain development during the pegboard task was calculated as changes in VAS slope.
Also, effect sizes for each group were calculated as changes in scores divided by their baseline standard deviations [ 33].
In this model, changes in serum creatinine were expressed as Δ creatinine, which was calculated as: Changes in creatinine = Highest serum creatinine value - Baseline creatinine.
One-way ANOVA was used to evaluate differences between groups at short- and mid-term follow-up for each outcome measure (differences were calculated as changes since baseline).
Responses to treatments were calculated as changes in respective parameters (e.g. FMD): 1-month values minus baseline values on day 1.
The differences between scores at pre- and post-treatment time points were calculated as change scores.
The results were calculated as change in percent.
In order to normalise the results, data were calculated as change relative to day 1.
Gestational weight gain was calculated as change from pre-pregnancy weight to weight at delivery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com