Sentence examples for be bound with high from inspiring English sources
Successful inhibitor design requires a region where small molecules or peptides can be bound with high specificity.
While PBPs often show a high degree of specificity and can discriminate between closely related compounds, OBPs appear to recognize a broader spectrum of odorants, suggesting that odor molecules may be bound with high affinity by one class of OBPs and with a lower affinity by another class [9].
For example, immunodominant antigens in the skin might be bound with high affinity in only certain MHC strains.
One possible explanation for this would be that BH4 must be present during protein synthesis to be bound with high affinity.
However, as mentioned above, because of the large excess of NOS over [H]-BH4, all label should be bound with high affinity, and no heterogeneity in BH4 dissociation is expected.
Exogenous glucosamine is bound with high affinity to glucose transporter GLUT-2 [ 1] and can induce insulin resistance in adipocytes [ 2] and skeletal muscle cells [ 3].
Iron exported from enterocytes or cells from the MYPS is bound with high affinity to transferrin (Tf), a glycoprotein produced in the liver and able to bind one or two iron molecules.
We employed only motifs that are bound with high confidence (P ≤ 10-3); notakingng into account conservation among other sensu stricto Saccharomyces species, since our interest in purely focused on Saccharomyces cerevisiae.
Recently we showed that nicked HJs are bound with higher affinity than intact HJs in the presence of a relatively low concentration of divalent metal ion [15].
Ten lipids were bound with higher affinity by D-4F, including arachidonic and linoleic acids, PGPC, POVPC, PEIPC, Kodia-PC, 13(S -HPODE, 12(S -HPODE 12(S -HETE and 9(S -HETE (Table 3).
Because tet-O is bound with very high affinity and specificity by the tet repressor (tet-R), the tet-O sequences in the HAC can be targeted with tet-R fusion proteins that inactivate the centromere and induce HAC loss.
