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In principle, parameters could be both essential and modulatory, depending on the perturbations in question.
The reported LC sequence was shown to be both essential and sufficient for formation of RNA granules through trapping of RNA binding protein-containing LC sequences, including FMRP.
This way, the dendritic distribution of mitochondria can be both essential and limiting for the support of synapses [ 13, 75, 76].
Surprisingly, however, we found that the C-terminal domain of Orc6 proved to be both essential and sufficient for Orc3 binding when co-expressed in insect cells.
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For me, it was both essential and unbearable viewing.
But while debt may be inevitable for many, keeping the cost of borrowing down is both essential and manageable.
Proving a drug's efficacy through clinical trials is both essential and expensive.
Proper formulation is both essential and critical for finding appropriate solutions to such problem.
Most feel that the time, money, and energy they spend on nurturing a network of professional and personal contacts are both essential and gratifying.
Michael Cox's introduction to The Oxford Book of Ghost Stories and his biographical study of MR James are both essential and enjoyable reading.
Generations of South Africans have told and retold the story of the Mendi, such that the details are both essential and pliable.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com