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Generally, we find that these motifs tend to be located in better conserved parts of peaks, and the motifs found within peaks tend to be better conserved than motifs found elsewhere in gene blocks (not shown), suggesting that occurrence in promoter regions, but not in non-peak portions of blocks, are under the most stringent selective pressure.
For instance, purine and pyrimidine patterns have been found to be better conserved than base composition in all domains of life [ 3].
Indeed, it seems that pathways may be better conserved than its individual components (i.e. genes and proteins; McGary et al., 2010; Subramanian et al., 2005), as groups of orthologous genes may continue to operate together between species.
We found a difference in the degree of conservation between female and male-biased genes, similar to studies showing that female-biased genes tend to be better conserved than male-biased genes [ 9, 14].
The fraction of shared orthologs between two circular genomes was found to be better conserved than the order of genes (Huynen and Bork, 1998), in which the fraction of shared orthologs between genomes was employed to measure genome evolution of nine prokaryotes.
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The conservation score measures the fractions of 7-mers that are better conserved than the motif, i.e. a conservation score of 1 means that the motif is better conserved than all 7-mers.
CSPs have only four conserved cysteines linked by disulfide bridges between neighboring residues [ 10] and are better conserved than OBPs across species [ 11].
Analysis of the consensus revealed that the dif XerD site is better conserved than the dif XerC site and that within both dif XerC/D boxes, the most conserved region is located in the inner part, near the central region.
An analysis of interdistances among cells in the three other quadrants shows that the mean interdistance between cones in the peripheral retina (about 20 µ) is better conserved than the corresponding value between rods (about 3 µ), proving the primary rod degeneracy.
The attC is better conserved than the attI [ 32] and has been well characterized in several species of Vibrio [ 33].
A conversion event produces a within-species alignment where one part is better conserved than other parts.
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