PSMA-based imaging agents described are based on molecules that differ in size, e.g. antibodies, nanobodies, aptamers and low molecular weight inhibitors of PSMA [ 116, 123– 123].
A common strategy to block Ras activation and signal transduction is based on molecules that interfere with the guanine exchange factors (GEF -promoted nucleotide exchanGEF -promoted
Our candidate gene selection was based on molecules that are known or likely to influence the regulation of HBV vaccine-induced immune responses such as those involved in pathogen uptake and recognition, antigen processing and presentation, as well as effector and memory T and B cell function (for full list see supplementary Table S1).
Biologic targeted therapy is based on molecules implicated in molecular pathways relevant to the biology of the breast cancer cell.
The reference data file is based on molecules and parent compounds carrying no charge and is derived from the MMD which contains an array of information from a wide variety of electronic resources.
The findings should be of broad interest to the community of biologists, as it includes elements of microbiology, signaling between bacterial and eukaryotic cells that is based on molecules not before known to carry out this function, and the evolution of multicellularity in the sister group to the animals, the choanoflagellates.
Our results show that the strategy to block virulence of human pathogens can be based on small molecules targeting motor proteins of bacterial secretory systems.
Ideally, these rules must be based on individual target-based known small molecule exemplars.
Geoffrey Porges, the biotech analyst at Bernstein, says Gilead "is based on one great molecule and one brilliant insight".
The multiple-molecule methods we describe are based on multiple-molecule similarities defined as between the query molecules and each molecule ℬ in the database.
