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These services can equally be based on large specialised parallel servers or a co-operating set of under-used workstations.
As an academic, my expectation when I joined the private sector was that the white papers and collateral released by companies in this space would be based on large sample sizes, best-in-class empirical methods and rigorous interpretation.
These findings caution that selection of molecular markers for epidemiological typing should be based on large and globally representative strain collections.
Yet, accurate ages can only be based on large numbers of complete mitochondrial genomes, and American mtDNA haplogroups were only poorly represented in the total database of >3000 complete mtDNA sequences until very recently.
However, future primary studies on IRR of peer reviews that could be included in later meta-analyses should be based on large sample sizes and describe the evaluation sheet/rating system for reviewers in detail.
The third generation of linkage map could be based on large number of SNPs.
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We argue that these conflicting results regarding the effectiveness of PTP-based measures are due to different understandings of which research designs should be used: Transportation research tends to be based on large-scale quasi-experimental designs whereas public health research tends to favor experimental designs such as randomized control trials (RCTs).
Future research that intends to more deeply assess causal impacts must be based on larger samples and panel data.
A more detailed investigation should be based on larger samples of particular phylogenies, especially to provide estimates of the population variance during evolution.
Future research should be based on larger samples and include longitudinal designs.
In the future, calculations should be based on larger populations, and should include such corrections.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com