Sentence examples for be based on altered from inspiring English sources

We found WMH more frequently in our migraine patients with elevated serum cholesterol and uric acid levels, and we speculate that if there is a relation between migraine and cholesterol and uric acids levels, this can be based on altered endothelial dysfunction and migraine attack frequency.

Many age-related differences in drug and toxicant responsiveness appear to be based on altered ADME (Table 1) (Birnbaum 1991; Clewell et al. 2002, 2004; Mayersohn 1994; O'Mahoney 2000; von Moltke et al. 1995).

Several mechanisms have been forwarded to explain this lack of response in ERα-positive patients, one being based on altered tamoxifen metabolism or bioavailability [ 3- 5].

This theory is based on altered vasomotor regulation, which leads to the formation of phakomas and the naevus flammeus [ 104, 115].

Although this complement of WNK8 target genes (which is based on altered transcript levels in the three mutants) is more stringently defined than the complement of the EDM2 target genes (which is only based on altered transcript levels in one mutant), the former is almost twice as large as the latter, suggesting that WNK8 may have a wider spectrum of biological roles than EDM2.

In our assays, memory performance is based on altered visual preference in walking flies, a task likely to be less demanding than the constant flight required for flight simulator learning.

Diagnosis of myxoedema coma was based on altered sensorium ranging from obtundation and stupor to coma, hypothermia (core body temperature of less than or equal to 35°C), a precipitating illness, and low serum level of total or free thyroxine (T4) (total T4 of less than 58 nmol/L and free T4 of less than 10.3 pmol/L, lower limit of reference range).

Existing chemical contraceptives for men under development are based on altering the levels of sex hormones circulating in the bloodstream in order to inhibit the natural state of male hyper-fertility.

The MoComp proposed is based on altering the signal phase history from every point target, so that it corresponds to that of a motion error free receiver trajectory.

The mechanism of action of tolcapone is based on altering levodopa pharmacokinetics, as well as reducing the levodopa metabolite 3-OMD.

Other rehabilitative interventions are based on altering knee biomechanics, which may influence the development and progression of knee OA [ 4, 23].