Several reports are published regarding these changes being based on alterations of general neurophysiological parameters.
Such individual differences in stress vulnerability are based on alterations in neural circuits/mechanisms designed to properly tune and terminate stress responses.
Still, of all the various psychiatric disorders, fear and anxiety are probably the most tractable scientifically because they are based on alterations normal brain functions that are beginning to be well understood.
Fourteen of the 27 included studies investigated mechanical, material, as well as morphological properties (i.e., stiffness, Young's modulus, and CSA), which is essential in order to clarify if a change in tendon stiffness was based on alterations of the material properties and/or tendon hypertrophy.
The metaplasia-dysplasia-carcinoma sequence, the most significant and frequent type of gallbladder carcinogenesis, is based on alterations to the epithelium of the gallbladder mucosa.
Therefore, it does not seem that the increased AP in Alk1 +/+ mice is based on alterations in renal function or structure.
Generally, it is believed that the beneficial effect of training on systolic- and diastolic function is based on alterations of the Ca2+ regulatory systems involved in the excitation-contraction coupling and relaxation processes [ 33].
Whereas the GCIG criteria are based on alterations in the numeric values of CA125, the ratio criteria include a time factor, thus reflecting the rate of decline in CA125 levels.
Two of these four approaches are based on alteration of the biocatalyst (either by protein engineering or metabolic engineering), resulting in an extra degree of freedom in the process design.
Most studies are based on alteration of the growth trajectory through changes in dietary intake [33], but methionine-induced alteration of growth relate to changes in resource allocation made by the individuals.
