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Up to that date, normally two years after manufacture, all the fluoride must be available to bind to tooth enamel, hardening it against the acid that causes cavities.
These proteins bind specifically to antibodies through their nonantigenic (Fc) regions, which allow the antigen binding sites of the immobilized antibody to be oriented away from the solid phase and be available to bind the target analyte.
This sets in motion a "competition" between the THC pre-coated on the sensor and THC in the saliva to bind with the antibodies; the more THC in the saliva, the fewer antibodies will be available to bind to the THC on the sensor surface.
In this scenario, in the absence of one or more qrr genes, increased levels of this putative transcription factor(s) would be available to bind and activate the expression of the remaining qrr promoters.
However, when HN cannot be released from the receptor due to the lack of NA, HN, in turn, would not be available to bind other ligands, such as erythrocytes.
In the absence of Bim (or Bax/Bak), more Bcl-2 may be available to bind IP3R at the ER, thereby reducing calcium release and T-cell activation in response to self-antigens, or antigens in general, but this concept awaits independent confirmation.
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Drawing on previous work by Jenkins et al. (2001) which showed that the binding site for haloalkane GAs in the GABAA receptor could only accommodate one molecule, they proposed that pressure reversal occurred when halothane aggregated, so fewer monomeric halothane was available to bind to the putative binding site.
This is because, only a very small percentage of binding sites are available to bind to interact with the transcription factors, as mentioned earlier in the limitation of regulatory networks section.
In the liver, diferric transferrin competes with TfR for binding to Hfe, and, when iron is increased, more Hfe is available to bind to TfR2; this complex, TfR2-Hfe, promotes HJV binding to BMP6, increasing hepcidin synthesis [ 34, 36].
These data are reasonable, indicating the presence of many active sites on LL and LA surface, which are available to bind with Cd II) ions at low concentration.
Transporters are critical for ensuring that receptors are available to bind glutamate during subsequent release events, as well as for limiting receptor activation so that excitotoxic damage does not occur.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com