Sentence examples for be attributed to variants from inspiring English sources

The variability in levels of serum MBL in lupus patients could be attributed to variants in the MBL 2 gene [ 31, 32].

Rare monogenic diseases cannot be attributed to variants that are common, though such variants may contribute to the risk of common complex diseases, or act as modifiers of rare disease.

In this study, we examined whether differences in TLR4 expression levels may result from TLR4 promoter sequence variation and if diversity of innate immune responses could be attributed to variant TLR4 expression.

To consider the possibility that high dN/ dS ratios might be attributed to variant calling on paralogous gene copies, we examined observed heterozygosity (HO) in high- dN/ dS genes versus all other genes.

The majority of AMD genetic risk is attributed to variants of several components of the complement cascade; of which CFH, CFB, CFI, C2, and C3 are differentially expressed in the wound response model.

A previous claim that haplotype-dependent mRNA levels cannot be attributed to intragenic variants and must therefore reflect the VNTR variability (Marchand and Polychronakos 2007; Pugliese et al. 1997; Vafiadis et al. 1997) is convincingly refuted by this and many previous studies (Furger et al. 2002; Kwek et al. 2002; Lu and Cullen 2003) (and references therein).

The result showed that 83% (standard error 37%) of the variance between crosses could be attributed to common, autosomal variants with minor allele frequencies >5%.

These observations collectively indicate that all of the recruitment can be attributed to different CXCL8 variants and not to spurious contaminants.

This hypothesis states that a complex disease can be attributed to multiple rare variants with relatively high risks, and it has attracted much attention in recent studies.

It has been estimated that 17.7% of variability in gene expression may be attributed to these DNA variants and, subsequently, a growing number of genic CNVs and increased global burden of CNVs have been linked to several complex disorders [ Stranger et al., 2007; Zhang et al., 2009; Girirajan et al., 2011].

Common diseases may be attributed to combinations of variant alleles, but there are few model systems where the interactions among such variants can be studied in controlled genetic crosses.