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By genetic analyses, this could be attributed to mutations either in the GLUT transporter sequence or in the genome of the yeast host.
Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2. Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques.
Continuous proliferation of cells in serum-free medium could be attributed to mutations of key genes (e.g., K-Ras).
Less than 40% of familial breast cancer can be attributed to mutations in the high-risk genes BRCA1 and BRCA2 despite their high penetrance [ 1, 2].
A large proportion of familial breast cancer (<40%) can be attributed to mutations in the high-risk genes BRCA1 and BRCA2 [ 1].
Many fixed allele-SNPs (i.e., not heterozygous within a line) could be attributed to mutations occurring along specific branches of the phylogeny (Table 5).
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It is unknown whether this isolate's failure to form biofilms can be attributed to mutation, perhaps post-isolation, or phenotypes segregating in natural populations.
In these cancers, CIN can often be attributed to mutation in DNA repair genes, suggesting that the drive behind tumor development is the increase in spontaneous genetic mutation resulting from a lack of appropriate management of DNA damage [ 48].
Thus, a change in genotype in a patient with Whipple disease must be interpreted as an infection with a different strain and cannot be attributed to mutation of the original strain.
Various diseases have been attributed to mutations of TRP channels.
Such three low-Cd mutants were attributed to mutations of OsNRAMP5 responsible for Cd transport in rice by sequence analysis (Ishikawa et al. 2012).
More suggestions(14)
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