The highly aggressive AML phenotype is attributed to further upregulation of MYB and miR-155 upon p53 loss, resulting in additional downregulation of PU.1 (50).
The enhanced oleophobicity can be attributed to the further lowering of surface energy by the presence of fluoropolymer.
However, as discussed earlier in optical analysis, optical absorption enhances with increase in deposition time, which may be attributed to the further aggregation of sensitizer in P-120.
This higher rate may be attributed to the further culture of Day 5 blastocysts in the blastocyst optimum culture medium, which significantly increased the number of cells in the ICM, thus isolation of ICM became much easier.
Since the lack of significant findings in some experiments, for instance memory retention in Novel object recognition task (Fig. 2D), might be attributed to suboptimal dosing, further studies will be necessary for pharmacological development.
If the mortality during the study interval exceeds this threshold, it will not be attributed to chance and further investigation of the research methodology will be warranted.
Unfortunately in the other cases, although some new peaks, with lower molecular ions compared to the parent prodrugs were identified, a conclusive structure could not be attributed to them and further analysis is undergoing.
The World Health Organization estimates that approximately 30,000 annual deaths can be attributed to OM, and further estimates that half of the world's burden of permanent, serious hearing loss (>175 million individuals) involves OM [ 4].
It has to be noted, that chronological age is not identical with biological age and it is conceivable that some of the discrepancy between predicted and real age can be attributed to this difference – further research might facilitate determination of the biological age for personalized medicine.
