20 Between 30% and 50% of variability in the response to warfarin is attributable to variants in two genes, CYP2C9 and VKORC1.
The still unexplained genetic variation in longevity might be attributable to rare variants or variants with small effects, which has previously been reported for other complex traits, such as Alzheimer's disease.
We aimed to investigate whether such infections could be attributable to a variant form of P malariae or a newly emergent Plasmodium species.
The lack of causative mutations in the remaining 15 PCD subjects might be attributable to overzealous variant filtering, but the cancer cohort experience suggested that this was unlikely to be a major factor.
Conversely this means the remaining variation in susceptibility could be attributable to rare variants.
The remaining variance (up to 44%%) may, in part, be attributable to rare variants, weakly correlated with the measured SNPs (Visscher et al. 2010).
A substantial proportion of the familial risk of breast cancer may be attributable to genetic variants each contributing a small effect.
In some cases the observed experimental heterogeneity can be attributable to pre-existent variant cells within tumor cell populations [ 18, 24], but even within groups of syngeneic animals treated with the same tumor cells, the numbers of resultant metastases can be quite variable [ 25, 26].
These inconsistent calls might be attributable to differences in the variant detection algorithm [ 4] as we used UnifiedGenotyper from GATK [ 22] whereas the 1000 bull genomes project used mpileup from SAMtools [ 46].
Although we did not identify rare variants disrupting candidate genes in this region in individuals with schizophrenia, rare phenotypes may be attributable to unmasking of such variants (McDonald-McGinn et al. 2013).
