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Since a kidney from a young deceased donor would probably be allocated to a young local candidate, young candidates in areas with long waiting lists would still be at a substantial disadvantage under the new proposal.
Michael P. Spies, the head of European operations for Tishman Speyer, declined to say what asking rents would be, except to say they would be at a "substantial discount" to rents in central Paris, which can exceed 800 euros a square meter (about $100 per square foot).
Parents who are free to choose characteristics for their offspring may be inclined to choose similarly, either because they agree (perhaps wrongly) that those characteristics are better, or because they worry their child will be at a substantial disadvantage relative to other children if they choose what is unpopular (or simply fail to intervene to ensure what is popular).
Gamers with some of the characteristics mentioned above were not necessarily addicts but appeared to be at a substantial risk of addiction.
As a result, even a geocoded location very close to or inside the correct parcel may be at a substantial distance from the actual school building(s).
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Political analysts initially pegged her as the underdog, not only because she was the challenger, but because she was at a substantial financial disadvantage.
In a statement, Kraft stressed its offer was at a "substantial premium" to Cadbury's share price prior to the US firm confirming its bid interest in September.
Also known as deep-value investors, members of this group say they will buy a stock only if its price is at a substantial discount to its true worth, including tangible assets, earnings and money in the bank.
With William Adelin dead, Henry had only one other legitimate child, Matilda, but as a woman she was at a substantial political disadvantage.
The findings showed that patients who had repeated PZQ treatments were at a substantial risk for developing CCA.
Therefore, older adults are at a substantial risk of dying by suicide compared to the younger age categories.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com