However, EXT can be associated with significant procedure-related morbidity.
Pharmacological treatments, mainly sedative-hypnotics and antipsychotics, are often used but can be associated with significant adverse effects.
For central lung tumours, very high SABR doses can be associated with significant toxicity.
These procedures can be associated with significant pulmonary complications, including atelectasis, pneumonia and respiratory failure.
Modifications of the BM can be associated with significant changes in protein content.
Surgical complications after breast reconstruction can be associated with significant morbidity, dissatisfaction, and cost.
Cervical pregnancy may be associated with significant vaginal bleeding, and, in severe cases, hysterectomy is required.
Chronic abuse can be associated with significant organ impairment, and, in rare cases, cardiac dysrhythmias and deranged end-tidal gas monitoring.
Interferon-induced ocular complications, including retinal ischemia and ischemic optic neuropathy, can be associated with significant visual loss.
However, there is concern that ovarian cystectomy might be associated with significant recurrence risk in patients with MCA.
Surgical management typically requires anterior decompression and reconstruction; however, these procedures can be associated with significant morbidity and mortality.
