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Human homolog mutations of many genes with photoreceptor-associated expression have been shown to be associated with retinal diseases including RP [27].
Although levels of SAA and CRP have been shown to be associated with retinal vessel dimensions (2), it is currently unknown whether this association differs between individuals with and without diabetes.
Epiretinal membranes have more evident depth, may obscure underlying retinal detail, may be associated with retinal striae, and can be associated with tractional forces that contribute to macular edema or (in extreme cases) tractional retinal detachment (Fig. 5).
Familial CCMs show autosomal dominant inheritance, and may be associated with retinal cavernous hemangiomas [ 4].
The postoperative decreases in VLA and increases in FBL after ERM surgery may be associated with retinal distortion relief.
Recently, Michaelides and Foster also suggested that angle-closure may be associated with retinal vein occlusions in retrospective case series with diverse ethnicity [ 10].
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In humans, mutations in CRX are associated with retinal degeneration diseases such as cone-rod dystrophy-2, retinitis pigmentosa (RP), and Leber congenital amaurosis (LCA) [6], [8], [9], [10].
It is unclear whether protein C deficiency is associated with retinal venous occlusive disease.
To investigate whether plasma pentosidine, a well-defined advanced glycation end product, is associated with retinal hemodynamic abnormalities in patients with type 2 diabetes.
The authors investigated whether arteriolar oxygen saturation (SaO2) and total cerebral blood flow (CBF), indicators of cerebral oxygen supply, are associated with retinal arteriolar or venular diameters.
To perform a quantitative trait locus (QTL) analysis and evaluate whether a locus between SIX1 and SIX6 is associated with retinal nerve fiber layer (RNFL) thickness in individuals of European descent.
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