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CCL2 has been shown to increase infiltration of tumour-associated macrophages (TAMS) in colorectal cancer and to be associated with progression of the cancer 22.
Therefore, increased expression of the UEAI-reactive molecule was related to transformation of colorectal epithelial cells and decreased expression appeared to be associated with progression and metastatic potential.
Its expression has previously been found to be associated with progression of the tumor invasion and metastasis [7], [8].
For genetic variations discovered to be associated with progression to AIDS-1987, sequelae including Kaposi's sarcoma (KS) and Pneumocystis carinii pneumonia (PCP) were tested in dichotomous case-case categorical and survival models.
Therefore, repeated episodes of ARF may be associated with progression to ESRD.
19, 20 These results suggest that Capn4 upregulation might be associated with progression of NPC.
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In sunitinib-treated patients pre-treatment NLR has been discussed to be associated with progression-free survival [12], and sunitinib even decreases NLR [13].
In a previous study, this polymorphism was found to be associated with progression-free and overall survivals in colorectal cancer [ 26].
Moreover, the expressions of miR-22 and miR-146a were identified to be associated with progression-free survival (PFS) while the expressions of miR-92a and miR-330-3p were identified to be associated with overall survival (OS) of pPCL patients, demonstrating their relevance in clinical prognostication in this aggressive form of plasma cell dyscrasia [ 86].
More recently, TLE3 was identified in a screen for genes causing estrogen independence in breast cancer cell lines and RNA levels further shown to be associated with progression-free survival in ER-expressing patients treated with tamoxifen as first-line treatment for metastatic disease [ 20, 21].
Deterioration of calf muscle pump function is associated with progression of chronic venous insufficiency (CVI).
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