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We hypothesized that phenols would be associated with earlier puberty, that phthalate biomarkers would be related to later pubertal timing, that phytoestrogens would be associated with later breast development, and that associations could be modified by obesity.
Extrauterine growth restriction is frequently observed in very preterm infants at the time of discharge from hospital, and has been found to be associated with later impaired neurodevelopment.
The use of a prospective longitudinal study meant that we were able to investigate factors earlier in life that may be associated with later headache diagnosis, without the problems of retrospective recall such as distortion or forgetting which may introduce bias.
This may be associated with later increased offspring risk of diabetes [44], and metabolic syndrome [49].
Meanwhile, our results suggested that MMP-2 may be associated with later stage of tissue repair.
We found depression to be associated with later smoking initiation.
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A second approach would add a number of preliminary end points (such as epigenetic modifications) and pathway measures (such as DNA methylation capability) onto the very early part of a 2-year rodent bioassay beginning with an in utero exposure; early biomarkers could then be associated with later-life disease.
Vondracek et al. (1986) found that patterns of vocational identity in adolescence are associated with later psychological well-being.
In contrast, both baseline symptoms and increase in symptoms were associated with later harmful alcohol use in females and these associations were not diminished by confounder adjustment.
Size at birth is associated with later cognitive development.
Bipolar disorder (BD) is associated with later sleep and daily activity (evening rather than morning chronotype).
More suggestions(17)
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Justyna Jupowicz-Kozak
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