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NLR family, pyrin domain containing 1 (NLRP1) gene on chromosome 17p13 is involved in the primary immune system and was shown to be associated with generalized vitiligo and other autoimmune diseases [[138]-[141]].
Mutations in NR3C1 have been previously demonstrated to be associated with generalized glucocorticoid resistance [ 53].
Classical cytotoxic chemotherapy has been traditionally considered to be associated with generalized immune suppression.
Interestingly, abnormalities of saccades appeared to be associated with generalized fatigue in patients with multiple sclerosis (Finke et al., 2012).
Rarely they can be multiple or diffuse as seen in hemangiomatosis or be associated with generalized angiomatosis syndromes.
Prolonged propofol administration may be associated with generalized seizures, increase carbon dioxide production, and hypertriglyceridemia [ 59, 60].
Similar(53)
3, 10 However, both oligocone trichromacy and RGS9/ R9AP-associated retinopathy are associated with generalized cone system dysfunction, with an undetectable light-adapted 30 Hz flicker electroretinogram and a severely reduced light-adapted 3.0 electroretinogram.
Positive responses are associated with generalized success and negative responses are related to depression and helplessness.
The febrile phase involves high fever, potentially over 40 C, and is associated with generalized pain and a headache; this usually lasts two to seven days.
The two most commonly prescribed oral retinoids, isotretinoin and acitretin, are associated with generalized muscle stiffness syndrome and myalgia in some individuals [93].
Larger retinal venular diameters are associated with generalized atherosclerosis, inflammation and cholesterol levels.
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