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Our case demonstrates that SEL may be associated with difficult lumbar puncture due to a dry tap.
So far, previous clinical researches and case reports have documented several factors to be associated with difficult PAC placement [5, 7, 9, 10].
Other metabolic disturbances that increase the work of breathing and that therefore may be associated with difficult weaning include metabolic acidosis and fever.
Although ICU-acquired weakness is the most frequent neurological disorder in the ICU, other neurological disorders may be associated with difficult weaning (reviewed in [ 44]).
The study reported an early presentation of AIS, which may be associated with difficult access to primary care in this city.
Antenatal anxiety has also been shown to be associated with difficult infant temperament [ 42] and emotional and behavioural difficulties in childhood [ 43– 43].
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Clinical data suggest that diaphragmatic dysfunction (DD) is associated with difficult weaning from mechanical ventilation.
Regarding the implant success rate in the present study, it must be considered that the lost implants were associated with difficult surgical conditions.
Therefore, in this patient, the SEL was thought to have caused the inability to obtain adequate CSF during lumbar puncture, and was associated with difficult spinal anesthesia.
Sleep problems are associated with difficult behaviors and family stress, and are often a focus of clinical attention over and above the primary ASD diagnosis.
Specifically, samples of urine, saliva and serum are associated with difficult sample matrices.
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