Sentence examples for be associated with debilitating from inspiring English sources
Unfortunately, the effectiveness of L-DOPA therapy often is limited and can be associated with debilitating side effects [ 54].
Such a selective activity profile might be most beneficial for the treatment of human malignancies wherein treatment with conventional chemotherapy is known to be associated with debilitating side effects directly linked to an adverse impact on the quality of life of the patients.
In addition, BM may be associated with debilitating neurological symptoms such as headaches, motor deficits, and seizures [ 8].
The development of CNS disease can be associated with debilitating neurological symptoms and poor survival [ 3, 4].
However, it may be appropriate to discuss PND or PGD in families affected by a particularly severe form of MKD or chronic infantile neurological, cutaneous and articular syndrome (CINCA) as these disorders can be associated with debilitating complications: blindness, deafness, mental retardation, ataxia and bone deformation.
Alterations in the morphology and viscoelastic properties of mRNP granules, due to mutations in resident proteins (e.g. hnRNPA1, FUS) are associated with debilitating neurodegenerative diseases [ 13, 42, 44, 45].
Moreover, RT is associated with debilitating early- and late-treatment-related toxicity, thus finding means to de-escalate therapy, while retaining/augmenting therapeutic effectiveness, is highly desirable.
This indicates that in a substantial number of cases SCCH is associated with debilitating limitations that affect the socio-economic situation of patients.
