Recently, HDAC4 was found to be associated with aggregate-prone mutant Huntington's disease associated products of the huntingtin gene (HTT) that have long polyglutamine stretches [ 3].
Specifically, we examine whether unemployment rates, labor force participation, and food stamp usage are associated with aggregate rates of child abuse and neglect (CAN) rates using state-level data.
Therefore, any extinction of the incident light higher than 320 nm is assumed to be scattered light that is associated with aggregate formation within the solution.
In severe EBS, the mutation is associated with aggregates of nonfilamentous keratin protein, and cell lines carrying such mutations show a constitutively activated stress response.
But in the last nearly 20 years, there has been a steady appreciation that canonical heat-shock induced proteins are associated with aggregates (Lindquist lab and others).
Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), are associated with aggregates that contain some of the RNA-binding proteins that are also found in stress granules.
Specifically, we found that changes in gene expression at the 4 h aggregate stage in chimeras may be associated with larger aggregate size in D. discoideum.
We hypothesised that this new level of quality management might be associated with the aggregate performance indicators on the patient level.
SCA3 thus becomes the first spinocerebellar ataxia to be associated with axonal aggregates.
EFHD2 is a calcium-binding adaptor protein that has been found to be associated with pathologically aggregated tau in the neurodegenerative brain in Alzheimer's disease and in a mouse model of frontotemporal dementia (Ferrer-Acosta et al, 2013b).
Such damage might be associated with protein aggregates, which have been shown to localise at the cell poles due to passive Brownian motion combined with size exclusion by the nucleoid, resulting unavoidably in preferential location at the old-pole [ 33, 65].
