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Second, H3K9Ac has been shown to be associated with actively transcribed genes in the schizont stage of the P. falciparum IDC [6].
As Abu-Farah and colleagues found histone methyltransferase activity to be essential for target gene upregulation [32], we also determined the extent of H3K4 as well as H3K36 methylation in neonatal Smyd2 cKO versus control hearts, as these histone modifications are generally believed to be associated with actively transcribed genes [30] [31], [48] [49].
This data underscores the idea that HOT1 might be associated with actively processed telomeres in a telomerase-positive context.
Lysine 4 and Lysine 36 methylation were only detected in HISTONE H3.2, suggesting that HISTONE variant H3.2 might be associated with actively transcribing genes.
An increase of astrocytes expressing GFAP can be associated with actively demyelinating through early remyelinating multiple sclerosis lesions (Schonrock et al., 1998).
Several factors, especially those that tend to be associated with actively transcribed genes or located at the proxy promoter such as H3k4me3 were more likely to be associated with the cCTCF-non-cohesin sites (Additional file 3: Figure S3).
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While AcH3 is associated with actively transcribed genes, to fully understand target gene activity or inactivity it is necessary to directly evaluate the expression of Stat3 and c-Myc targets in ES cells.
In Drosophila, ASH1L activates ultrabithorax expression, and mammalian homologues have been associated with actively transcribed genes.
Acetylation of lysine 9 on histone H3 has been associated with actively transcribed genes [3], [4], but the degree of association is unknown at the genome-wide level in leukemia patients.
These results supported the notion that basonuclin was associated with actively transcribed rDNA.
Acetylation of Histone H3 (AcH3) is associated with actively transcribed euchromatic chromatin regions [26].
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