Our study was aimed to investigate if modifications in cancer cell morphology are associated to relevant transition in tumour metabolome, analyzed by nuclear magnetic resonance spectroscopy and principal component analysis.
Both regulations were associated to relevant biological functions, the former playing a role in cancer proliferation [ 28], while the latter in vertebrate brain physiology [ 26].
Therefore we might hypothesize that certain changes in morphology might not compulsory be associated to clinically relevant cell transformation.
Low NS was previously identified as a characteristic of the non-responder group in the short term [ 43]; our data support this results, in this case predicting the long-term outcome: initial low NS scores were associated to the worsening of relevant clinical symptoms (BD, ASC, IR and SI).
Data as constraining affordances answers waiting for the relevant questions are transformed into factual information by being processed semantically at a given LoA (alternatively: the relevant question is associated to the right answer at a given LoA).
Several clinico-pathological entities have been associated to B. ceti infection in a relevant fraction of the stranded dolphins and porpoises [ 5], with neurobrucellosis being one of the most significant signs present [ 8, 12, 11].
Since STIs are increasing all over the world and STIs are associated to having more lifelong sexual partners, and the latter with earlier sexual initiation, the study of whether certain messages are associated to earlier sexual initiation is relevant across different cultures and countries.
In patients with septic shock after the initial phase of hemodynamic resuscitation, passive exercise does not seem to be associated with relevant changes in microcirculation or in the systemic hemodynamics.
In addition, ageing showed to be associated with relevant changes in thyroid function.
The frequent use of GCs as a "bridge therapy" in patients with early arthritis does not seem to be associated with relevant loss of bone mass.
