Optimism, a personality trait defined as holding general positive beliefs regarding the future, has been associated to improved physical health and longevity.
In contrast, HDAC 1 expression in breast cancer is associated with estrogen receptor/progesterone (PR) expression at the earlier stage of disease (T as well as N classifications) and improved patient survival response to tamoxifen (Bicaku et al. 2008), and HDAC 6 expression is associated to improved patient survival (Zhang et al. 2004).
Angiogenesis and apoptosis are primordial features of malignant tumours, constituting attractive therapeutic targets; drugs that inhibit angiogenesis or promote apoptosis could be associated to cytotoxic agents to improve antitumoral therapy.
Increased levels of adropin in transgenic mice were found to be associated with improved response to diet-induced obesity, insulin resistance, and glucose tolerance [ 54].
Similarly, Molinari et al. [ 48] found hypermethylation of the TIMP3 tumour suppressor gene appeared to be associated with improved response to 5-FU-based neoadjuvant chemoradiotherapy.
Both have been shown to be associated with improved prognosis attributed to increased susceptibility to radiotherapy.
As different compounds in human breast milk are shown to be associated with improved baby health, formula manufacturers rush to add them to their products, but there is still much we don't know about the specifics of the interaction between breast milk and baby.
One of the most commonly reported factors to be associated with improving retention and follow-up is the attention afforded to subjects during their participation in the study [ 4].
The somewhat right-lateralized CNV bore the clearest hallmarks of this intentional preparation: Switch-specific modulations of this component were restricted to the location task, mirroring the greater cost of switching to this task, and increases in its amplitude tended to be associated with improved performance.
49 Other factors contributing to the placebo effect in our trial include blinding of participants, a treatment protocol involving considerable interaction with the therapist (10 individual sessions), and the fact that most (90%) participants expected to gain a moderate to large benefit from active treatment (given that positive expectations are known to be associated with improved outcomes 50).
