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This gene was also found to be associated to human inflammatory disorders [5].
Circadian genes with a polymorphism previously reported to be associated to human bipolar disorder include CLOCK [54], and NR1D1, ARNTL and PER3 [55]–[57].
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In this way, urban contexts can be learned and recognized automatically, that is, sensor observations can be associated to human-defined context labels using machine learning and reasoning techniques.
We have genotyped nsv436327, a common CNV mapping SIRPB1 intron 1 that has been associated to human personality behavior.
To date, KI and WU polyomaviruses (KIPyV and WUPyV) have not been associated to human diseases.
So far KIPyV and WUPyV have not been associated to human diseases, while MCPyV was discovered in Merkel Cell carcinomas and may have neuroepithelial cell tropism.
Circadian gene polymorphisms in CLOCK and VIP [38], [39], and NR1D1, ARNTL and PER3 [40]–[43] have previously been associated to human bipolar disorder.
Further work will be needed to better understand the function(s) of DCLK1 in cognitive processes, and its role in synaptic plasticity, especially since other related genes (CAMK2G and CAMTA1) have also been associated to human memory performance [60], [61].
Moreover, the mir-200 family members have recently been associated to human breast cancer [ 35- 39] and their overexpression was shown to promote the mesenchymal-to-epithelial transition [ 40].
The p63 transcription factor, homolog to the p53 tumor suppressor gene, plays a crucial role in epidermal and limb development, as its mutations are associated to human congenital syndromes characterized by skin, craniofacial and limb defects.
Some of them have been also found to be associated to different human diseases.
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