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This result is attributed to efficient markets.
A step ahead, SMAR1 was found to be essential for efficient recruitment of Ku70 to damage-associated chromatin fraction to carry out repair, as evidenced by increased chromosomal aberrations and defective DNA repair upon SMAR1 knockdown.
Achieving these goals means that the state is able to design efficient control mechanisms, which certainly has an associated cost.
If selection is acting to control efficient splicing, it should prevent synonymous mutations that might disrupt the splicing-associated motifs in exons, such as ESEs.
We're going to be efficient".
These were proved to be efficient.
Sequencing restriction-site associated DNA (RAD) might be an efficient strategy to simplify genotyping.
As ATM-mediated DNA damage signaling is considered to be indispensable for efficient recruitment of repair proteins to DSB sites, we wondered whether the redistribution of SMAR1 to damage-associated chromatin fraction is ATM-dependent.
One challenge is to remain energy efficient.
You have to be efficient to survive.
This permanent growth arrest would be an efficient barrier to melanoma development that may not be triggered by melanoma-associated p16INK4a variants.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com