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A collection of approaches, and a focus on critical thinking and problem solving, will be used to show how fundamental, highly-significant biological problems are "cracked open". Reading will be assigned from a mix of classic and current peer-reviewed papers selected by the instructors.
In the TOF traps reported by Schowalter et al. and Deb et al. [18, 21], all ion masses can be assigned from a single experiment but these setups require more complicated RF electronics.
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With the deoxyribose H1′ assignments in hand, the remainder of the deoxyribose protons were assigned from a combination of NOESY and COSY data.
The parameter, ν, was assigned from a G 0.5, 1) distribution.
The P resonances were assigned from a P H3′ HMBC spectrum.
Exposure values were assigned from a PM2.5 surface derived from a geostatistical model.
Aromatic sidechain resonances were assigned from a (HB CB CGCD HD spectrum.
For subjects actually given RT, a dose was assigned from a χ2 distribution with four degrees of freedom.
This model is also implemented in the program BEAST [ 15] although the standard deviation of log rate, rather than σ, is assigned from a user-defined distribution.
The initial expression rates of the TFs in each cell were assigned from a normal distribution with μ = 1.5 and sd = 1.
The randomisation codes were assigned from a computer-generated list held by the study sponsor (AstraZeneca R&D, Mölndal, Sweden); code envelopes were used as an emergency unblinding tool.
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