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Exact(23)
Genes annotated to encode a transcriptional regulator (HMPREF0421_20023), a toxin-antitoxin (TA) system toxin (HMPREF0421_20022) and two permeases map within the transposon; the remaining genes were unable to be assigned a function.
Comparative analyses of Plasmodium genomes and genomes of other organisms have greatly improved the identification and assignation of putative functions to Plasmodium genes, and these analyses have revealed that about 50% of malaria parasites genes cannot be assigned a function by homology and it is therefore likely that many of these genes perform functions that are unique to Plasmodium.
Thus, 528 genes could be assigned a function using the KEGG databases.
It should be recognized that every component of the unit formula that can be assigned a function is important.
The majority of the unmatched transcripts (n = 144) could not be assigned a function using the non-redundant databases (tBLASTx, E-value <10-10 <10-10
The remaining 28.1% H. bacteriophora distinct ESTs represented novel genes yet to be assigned a function, demonstrating enormous novel gene discovery potential of this EST study.
Similar(37)
Prior to the release of the sequence, only a few genes were assigned a function each year.
Of the 2,122 CDS, 1,387 (65%) were assigned a function through sequence analysis.
Again, a huge proportion of proteins (10 out of 26) has not been assigned a function yet.
Of those, 4,518 CDS were assigned a function using one of five evidence classes, while 1,274 and 611 CDS remained, respectively, 'conserved hypothetical' or 'hypothetical'hypothetical
This is potentially important because it is usually assumed that when genes are assigned a function, it is due to either a valid prediction or a false positive due to "promiscuity" or other issues with the data.
More suggestions(17)
be assigned a propensity
be assigned a study
be assigned a risk
be assigned a value
be assigned a weight
be assigned a grade
be assigned a guardian
be assigned a number
be assigned a dissimilarity
be assigned a priority
be assigned a storage
be assigned a spaceflight
be assigned a case
be assigned a designer
be assigned a color
be assigned a date
be assigned a fool
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com