Habitat quality was assessed using relevant variables based on published habitat-associations for each species or group.
Pain and stiffness will be assessed using the relevant subscales of the WOMAC [ 25].
Sports and recreation function, symptoms and knee-related quality-of-life will be assessed using the relevant dimensions of the Knee Injury and Osteoarthritis Outcome Score (KOOS) [ 26].
Predictive accuracy of the models and most relevant genes will be assessed using re-sampling methods (e.g. bootstrap) [ 42].
Risk of bias in included trials was assessed using the relevant Cochrane Collaboration's tool.
The quality of included studies was assessed using the relevant CASP appraisal tools.
Violence was assessed using the relevant section from the Californian Perinatal Assessment[ 11, 12].
Study quality was assessed using the relevant tools from Critical Appraisal Skills Program (CASP) or the STROBE document as appropriate to the study type [ 19].
History of emission trading and the concept of GHGs were assessed using previous and relevant literature materials.
CHD-FA toxicity was assessed using an orally relevant epithelial cell line to determine whether there were any detrimental effects from the compounds tested prior to immunomodulatory investigations.
