For each ampoule, viability was assessed on small aliquots of cells by propidium iodine staining; also the extend of DNA fragmentation was assessed with Comet essay in every replicate.
Independent sample sets must be used to validate the prognostic and predictive power of biomarkers particularly when many biomarkers are assessed on small sample sets.
This in turns indicates that aquaculture accidental releases should be more tightly controlled and their potential genetic impacts be assessed on a smaller scale, ideally at the population level.
Borthwick will be assessed on Monday.
Variables of interest such as biomass or carbon stock are assessed on a small sample of field plots, and these data are combined with the more densely-sampled earth observation data using statistical estimation procedures in order to generate estimates.
Bulk powder flow and tabletability were assessed on a small scale using ring shear tester and using a single punch compaction simulator, which can be easily integrated during the process of solid form screening activity for early preformulation studies.
Comparison with other tools, which are not available for downloading and hence with which it is not possible to perform an extensive benchmark, was assessed on a well-annotated small subset of sequences extracted from Uniref50 (release 13.0, March 2008).
Publication bias was assessed on the assumption that smaller studies are more likely to be published if they suggest elevated risks.
The use of model polystyrene nanoparticles in this study allows us to hypothesize how fundamental properties may affect degree and route of uptake of nanoparticles; however, it is important that uptake of nanoparticles is assessed on an individual basis as even small changes in size and charge, along with particle composition could alter the end points measured in this study.
Apoptosis and mitosis were assessed on a cell positional basis in small and large intestinal crypts of p53 wild-type and p53 null mice 6, 12, 24, 36, 48 and 72 h after the administration of high (200 mg kg−1) or low (40 mg kg−1) dose 5-FU±250 5-FU±250PDTC.
