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The primary outcome will be assessed between groups using a logistic regression model.
Changes over 3 months will also be assessed between groups using a MANOVA (α = 0.05) with independent-samples t-tests for post-hoc analysis.
Healthcare resource utilisation associated with the prevention of secondary VTEs will be assessed between groups for a reference country using non-parametric statistical techniques such as quantile regression analysis.
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Odds ratio for structural progression (JSN and mTSS) were assessed between group 4 and the other groups.
No significant difference in hamstring muscle stiffness can be assessed between both groups.
Also no significant changes in bone area/total area ratio were assessed between the groups.
Linear trends were assessed between smoking groups per end point by contrasting parameter estimates calculated from the models.
A significant variation was assessed between both groups in terms of creed towards equal ef-ficacy of p.o. and i.v. drugs (p < 0.0001).
Analysis of variance with appropriate post-hoc pairwise comparisons will be used to assess between-groups differences for continuous data.
Two-way ANOVA was performed to assess between-group differences, and Bonferroni correction was applied for multiple comparisons.
At the end of the study, recurrence will be assessed and compared between groups.
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